Why is duodenal ulcer common in males?

Why is duodenal ulcer common in males?

Duodenal ulcers usually appear between ages 30 and 50 and are more common in men than women. Stomach ulcers tend to occur later in life, after age 60, and affect women more often than men. The cause of most stomach and duodenal ulcers is infection with a type of bacteria called Helicobacter pylori.

Is PUD more common in men?

The prevalence of peptic ulcer disease has shifted from predominance in males to similar occurrences in males and females. The lifetime prevalence is approximately 11%-14% in men and 8-11% in women.

How does gender contribute to peptic ulcer disease?

These data show that the male predominance in peptic ulcer disease has changed. The male to female ratio is now 1.0 for self-reported period prevalence, and 1.3 for hospitalization and mortality. Ulcer prevalence rates for women have increased whereas rates for men have decreased.

Why do ulcers occur in the duodenum?

The main cause of this damage is infection with bacteria called Helicobacter pylori, or H. pylori. The bacteria can cause the lining of your duodenum to become inflamed and an ulcer can form. Some medications can also cause a duodenal ulcer, particularly anti-inflammatory drugs such as ibuprofen and aspirin.

What causes peptic ulcer?

The most common causes of peptic ulcers are infection with the bacterium Helicobacter pylori (H. pylori) and long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve).

What is the difference between gastric and duodenal ulcer?

A peptic ulcer is a sore on the lining of your stomach or the first part of your small intestine (duodenum). If the ulcer is in your stomach, it is called a gastric ulcer. If the ulcer is in your duodenum, it is called a duodenal ulcer.

Why are duodenal ulcers relieved by eating?

Duodenal ulcers tend to cause abdominal pain that comes on several hours after eating (often during the night); this is due to the presence of acid in the digestive tract without a food “buffer.” Eating or taking an acid-reducing medication may relieve symptoms.

Is peptic ulcer genetic?

There has also been some evidence that genetic factors play an important role in the etiology of peptic ulcer disease. However, the pattern of inheritance is not simple mendelian and the genetic basis is multifactorial. Risk factors for peptic ulcer include cigarette smoking and nonsteroidal anti-inflammatory drug use.

Why does stress cause peptic ulcer?

The stomach naturally produces acid to help digest food. When the stomach’s acidic environment changes or becomes too acidic, a person may develop symptoms of an ulcer. In people under severe physiological stress , ulcers may result from changes in the body’s pH. A Helicobacter pylori (H.

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