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Does methotrexate cause weight gain and bloating?

Does methotrexate cause weight gain and bloating?

As helpful as this medication is, those taking methotrexate may experience some side effects, including nausea and vomiting, mouth sores and ulcers, headaches, and fatigue. 1 Research has shown that using this drug can also result in weight gain.

Can you lose weight after methotrexate?

This medication is a disease-modifying antirheumatic drug. It can cause diarrhea, nausea, and an upset stomach, any of which may lead to weight loss. The study examined weight gain and weight loss in more than 30,000 people who were taking RA medication, such as methotrexate, prednisone, or leflunomide.

Does methotrexate make you hungry?

Mouth lesions, low blood counts, poor appetite, nausea, and abdominal discomfort are the most common side effects of methotrexate. Tiredness, dizziness, skin rash, hair loss, and increased susceptibility to infection have also been reported.

Can methotrexate cause bloating?

This medicine may cause stomach bloating and gas. — Try to avoid foods (such as beans, raw vegetables and carbonated beverages) that cause gas.

Does methotrexate suppress appetite?

Patients who stopped taking methotrexate reported having substantially more gastrointestinal issues — including nausea, abdominal pain, and loss of appetite — from methotrexate than current users did. Just 26 percent of current MTX users reported nausea, compared with 40 percent of those who used it previously.

How safe is methotrexate?

Although originally designed as a chemotherapy drug (using high doses), in low doses, methotrexate is a generally safe and well tolerated drug in the treatment of certain autoimmune diseases. Because of its effectiveness, low-dose methotrexate is now first-line therapy for the treatment of rheumatoid arthritis.

Can methotrexate cause cancer?

Ironically, a number ​of studies have suggested that methotrexate may, in fact, increase the risk of cancer in people with RA, including melanoma, leukemia, myeloma, lung cancer, and lymphoma.

Does methotrexate cause depression?

Unfortunately methotrexate has been known to indirectly cause bad thoughts. This is a tricky medication. I often talk about the side effects of this drug and it’s vicious cycle. Here’s what happens; methotrexate can cause severe fatigue, severe fatigue can cause depression.

Can methotrexate cause diarrhea?

Methotrexate Side Effects. Because methotrexate is such a strong medication, it has the potential to cause severe diarrhea, frequent infections, lung damage, and other serious side effects. Methotrexate use is generally reserved for severe situations in which a person has not responded to other medications.

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